Ginkgo Biloba Research Today is a free monthly online journal that collates and summarizes the latest research about Ginkgo Biloba, including details on ginkgo biloba, herbal remedies, side effects, benefits.

Isolation and purification of ginkgo flavonol glycosides from Ginkgo biloba leaves by high-speed counter-current chromatography.

Zhang Q, Chen LJ, Ye HY, Gao L, Hou W, Tang M, Yang G, Zhong Z, Yuan Y, Peng A

Institute for Chemical Engineering, Sichuan University, Chengdu, China.

A high-speed counter-current chromatography method was developed for the separation and purification of bioactive flavonol glycosides from a crude ethanol extract of Ginkgo biloba leaves. The separation was performed with a two-phase solvent system composed of n-hexane-butanol-ethyl acetate-methanol-0.5% acetic acid (1:0.5:3.5:1:4, v/v) and three pure compounds were eluted in high purities in a one-step separation. Their purities were determined by HPLC and identified by MS,( 1)H-NMR, and( 13)C-NMR.

Published 16 August 2007 in J Sep Sci, 30(13): 2153-9.
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